The basal ganglia and apraxia

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The basal ganglia and apraxia.

Ever since Liepmann's original descriptions at the beginning of the century apraxia has usually been attributed to damage confined to the cerebral cortex and/or cortico-cortical connecting pathways. However, there have been suggestions that apraxia can be due to deep subcortical lesions, which raises the question as to whether damage to the basal ganglia or thalamus can cause apraxia. We theref...

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Limb apraxia in patients with damage confined to the left basal ganglia and thalamus.

Limb apraxia was investigated with standardised tests in 14 patients whose CT scan provided evidence of a vascular lesion confined to the left basal ganglia, or the thalamus, or both, and not involving the cortex or adjacent white matter. Five patients were severely impaired in imitating movements and pantomiming object use. Four of them also performed poorly when tested with real objects. In t...

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Stuttering and the basal ganglia

Based on personal experiences I have felt that the lack of real knowledge about the underlying mechanisms of stuttering is a problem in many ways. It makes it more difficult to treat, it leaves the field open to unfounded speculations, and it makes it difficult for persons who stutter to reach self-understanding. For this reason, I changed my vocation from engineering to research on the nature ...

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The Basal Ganglia

Progress in our understanding of the mechanisms underlying the cardinal motor abnormalities of Parkinson’s disease (PD), in particular akinesia and bradykinesia and their treatment, has been remarkable. Notable accomplishments include insights into the functional organization of the basal ganglia and their place in the motor system as components of a family of parallel cortico-subcortical circu...

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The basal ganglia

The basal ganglia, said Kinnear-Wilson in the 1920s, have all the clarity of a dark basement. And so it has remained for the better part of a century. There are now major new ideas about what these deeplying structures in the forebrain may be doing. Lesions of the basal ganglia lead to devastating motor disorders, including Parkinson’s disease and Huntington’s disease. In addition, the basal ga...

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ژورنال

عنوان ژورنال: Brain

سال: 1996

ISSN: 0006-8950,1460-2156

DOI: 10.1093/brain/119.1.319